LZTS2 and hepatocellular carcinoma: Moreover, LZTS2 expression in HCC-1937 and MDA-MB-231 cells was increased by co-transfection of a miR-9-5p inhibitor (0.22 ± 0.03 vs. 1.28 ± 0.03, 0.23 ± 0.01 vs. 1.28 ± 0.05, both P < 0.001), which was consistent with the result of the luciferase reporter assay (Fig. 4g).