Eotaxin/CCL11 (25.5, 10.4–62.2 vs 12.5, 3.8–56.4; p = 0.001), GM-CSF (10.4, 3.1–25.1 vs 6.9, 0.0–26.1; p = 0.01), GRO/CXCL1 (69.7; 0.0–895.6 vs 9.7, 0.0–249.0; p = 0.041), IL-10 (7.7, 0.0–41.3 vs 0.0, 0.0–5.2; p = 0.003), sCD40L (24.2, 0.0–226.5 vs 5.5, 0.0–229.2; p = 0.001), IL-1RA (23.5, 0.0–93.5 vs 0.0, 0.0–36.6; p = 0.0005), IL-1α (8.6, 0.0–55.9 vs 0.0, 0.0–31.2; p = 0.003) and VEGF (382.5, 0.0–1078.0 vs 200.8, 63.1–461.5; p = 0.01) levels have been increased in RA individuals (Fig. 2). The gene discussed is IL1R1; the disease is rheumatoid arthritis.