DNM2 and neoplasm: For instance, in cervical invasive squamous cell carcinoma, Lee et al. found that inhibiting the expression of the DNM2 gene can promote the overexpression MMP2 (the main structural component of the basement membrane), leading to the easy passage of tumor cells through the basement membrane of epithelium, surrounding matrix, and into blood vessels or lymphatic vessels, as well as metastasis to other sites to form new tumor lesions [13].