PTPRC and diabetic foot: Loretelli et al. (2020) found that the topical application of embryonic stem cell extracts (EXTs) in diabetic foot mice can promote wound healing of diabetic foot, which is accompanied by a decrease in CD45+ inflammatory cells and interferon-γ (IFN-γ), while an increase in regulatory T cells (Tregs), proliferating Ki-67+ cells, and the endothelial cell marker CD31.