ERBB2 and breast carcinoma: In terms of breast cancer cells, MCF-7 (HR-positive), SKBR3 (HER2-positive), and MDA-MB-231 (TNBC) depend on glycolysis to fulfil up to 25, 50, and 75% of their ATP requirements, respectively (Wu et al., 2016; Louie et al., 2020), suggesting that the dependencies of energy production may differ among breast cancer phenotypes, as well as genotypes.