In this study, the transcriptional expression levels of three lncRNAs namely colon cancer associated transcript 2 (CCAT2), HULC, and FOXCUT, and the effect of NaBu on cell cycle control, apoptosis, and expressions of these lncRNAs were evaluated in two prostate cancer cell lines, PC-3 and LNCAP. Here, HULC is linked to Familial prostate cancer.