CEBPA and acute myeloid leukemia: In 2010, a report based on one member of this family (III-45) was diagnosed as AML carrying a single heterozygous base pair deletion of the N-terminal (c.68delC) in somatic sample and a probable acquired three-base pair duplication (c.937_939dupAAG) in the C-terminal of CEBPA in a proportion of peripheral blood cells, indicating familial AML with CEBPA mutations (38).