SRSF1 (serine/arginine-rich splicing factor 1) promotes proliferation and injury-induced neointima formation in vascular smooth muscle cells (Xie et al., 2017), and it could promote tumorigenesis through regulation of alternative splicing in colon cancer (Chen et al., 2017), glioblastoma (Zhou et al., 2019), and other cancers. This evidence concerns the gene SRSF1 and malignant colon neoplasm.