It is worth noting that the LBC group also exhibits significantly reduced levels of expression of TNF-α, NF-κB, MYD88, IL-1β, and IL-6 (TNF-α, NF-κB, p < 0.01; MYD88, IL-1β, IL-6, p < 0.05). Here, TNF is linked to CDH1-related diffuse gastric and lobular breast cancer syndrome.