PRL and post-traumatic stress disorder: In the reduced effect of the EE in PTSD fear behavior, it was shown that the Cg1 and IL (but not the PrL) of the mPFC were increased in the c-Fos expression, and it indicated that after chronic EE exposures, the mPFC's executive and inhibitory functions interfered with the activity of the amygdala's BLA, which presented decreases in the c-Fos expression.