We find that the majority of the top markers for normal ductal cells in cancerous patients are mitochondrial genes (MT-ND2, MT-ND1, MT-ND4, MT-CO1, MT-ND5, MT-ATP6, MT-CO3, MT-CYB, MT-ND3, MT-CO2, MTRNR2L12, MT-ND6, and MT-ND4L), supporting previous research that mitochondrial metabolic reprogramming may be crucial to the progression of pancreatic cancers (Reyes-Castellanos et al., 2020). The gene discussed is MT-ND4; the disease is familial pancreatic carcinoma.