STAT3 and granular corneal dystrophy type II: Moreover, K17 enhanced T cell migration by upregulating CCL20 expression in keratinocytes in a process dependent on K17 translocation and interaction with signal transducer and activator of transcription 3 (STAT3) and mediated by the NLS and NES sequences of K17, which then drives T cell infiltration and contributes to ACD development.