TIMP1 and interstitial lung disease: Serum TIMP-1 was significantly higher in patients with ILD, compared to the matched group of patients without ILD [109.45 (93.05–200.09) vs. 65.50 (40.57–110.73), p = .007], while no statistical difference was found in PIIINP, HA, and ELF score (p = .412, p = .285, p = .215, respectively; Table 5).