They displayed increased visceral fat (P = 0.048), worse glycemia (HbA1c; P = 0.005 and fasting plasma glucose; P = 0.006), higher plasma concentration of liver enzymes (aspartate aminotransferase, alanine aminotransferase and γ-glutamyl transferase; P < 0.001) and increased prevalence and severity of hypertension (P < 0.001) (Supplementary Tables 1 and 2). The gene discussed is GPT; the disease is Hypertension.