WWTR1 and cyst: The average 2KW/TBW ratio in the early stage was similar between TAZfl/fl (wild-type, WT) and TAZfl/fl:KSP-cre (TAZ cKO) mice (Supplementary Fig. 1a), but the ratio in TAZ cKO mice was higher in the 36-week-old late stage than in the early stage, indicating that cyst formation was delayed.