As shown in Fig. 1a, the qRT-PCR results demonstrated that the mRNA expression levels of canine CD20 were significantly higher in B-cell lymphoma samples when compared with samples derived from healthy lymph nodes and non-B-cell lymphoma, including T-cell and non-B and non-T cell lymphoma samples (p < 0.05). Here, MS4A1 is linked to B-cell non-Hodgkin lymphoma.