HSPA1A and osteoporosis: To this end, we used a set of publicly available genomics data deposited in GSE (accession no. GSE7429), where DNA microarray experiments were performed using circulating B cells obtained from 10 postmenopausal women.39 In this dataset, the HSP70 (HSPA1A) gene expression level was positively associated with the BMD Z-score, suggesting that HSP70 might be a potent therapeutic target for osteoporosis (Fig. S7).