IMMT and neoplasm: As a result, Mic60-depleted tumor cells exhibited decreased oxygen consumption rates (SI Appendix, Fig. S2C), with lower basal and maximal respiration (SI Appendix, Fig. S2D), reduced adenosine triphosphate (ATP) production (SI Appendix, Fig. S2 E and F), and increased phosphorylation of AMPK, a marker of cellular starvation (SI Appendix, Fig. S2G).