When analyzed in patient samples of pancreatic ductal adenocarcinoma (PDAC), Mic60 expression ranged from focal perinuclear distribution in normal pancreatic acinar cells to disordered, submembranous or linear staining in in situ and invasive neoplastic epithelium to absence in poorly differentiated (basaloid) carcinomas by IHC (Fig. 1C). This evidence concerns the gene IMMT and pancreatic ductal adenocarcinoma.