IMMT and neoplasm: Immunohistochemical (IHC) staining of a universal tumor microarray (TMA; n = 5 to 8 cases per tumor type) gave similar results (Fig. 1A), where Mic60 expression was reduced in colorectal adenocarcinoma (COREAD) and glioblastoma (GBM), unchanged in breast (BRCA) and prostate adenocarcinoma (PRAD), or increased in lung adenocarcinoma (LUAD) compared to adjacent normal tissue (SI Appendix, Fig. S1B).