PIK3CA and sarcopenia: According to the results of GO and KEGG enrichment analyses, sarcopenia related pathogenic gene products primarily involve in aging and inflammation related signal pathways, such as longevity regulating pathway (hsa04211), cellular senescence (hsa04218), TNF signaling pathway (hsa04668), IL-17 signaling pathway (hsa04657), EGFR tyrosine kinase inhibitor resistance (hsa01521), PI3K-Akt signaling pathway (hsa04151), and endocrine resistance (hsa01522) et al..