AR and prostate cancer: In prostate cancer, TAD 1830 (Chr2:63,010,000 – Chr2:63,160,000) contains both rs721048 and enhancer 406,774, TAD 8618 (Chr8:128,410,000 – Chr8:128,490,000) contains both rs6983267 and AR binding site, and TAD 16953 (ChrX:66,530,000 – ChrX:67,270,000) contains both rs6152 and enhancer 2,765,787.