Restimulation of expanded TILs with autologous tumor cells revealed that GEN1046-expanded CD8+ TILs contained greater proportions of cells that upregulated 4-1BB and IFNγ/CD107a upon restimulation compared with atezolizumab and IL2 alone, which was dependent on MHC I (Fig. 3C). The gene discussed is IFNG; the disease is neoplasm.