According to the World Health Organization (WHO) (2016), these neoplasms have been divided into three main subgroups based on JAK2/CALR/MPL mutation; that is, Essential thrombocythemia (ET), polycythemia vera (PV), and primary myelofibrosis (PMF), and four clinicopathologic conditions including chronic myeloid leukemia (CML), chronic neutrophilic leukemia (CNL), chronic eosinophilic leukemia, and unclassifiable (MPN‐U).1, 2, 3, 4, 5, 6. This evidence concerns the gene CALR and essential thrombocythemia.