In multivariate analysis (P, beta [SD beta]), sFasL (P = 0.02, 0.99 [0.41]) and GGT (P<0.001, 0.74 [0.21]) were both significant predictors of AD during the follow-up of patients with CLD. The gene discussed is FASLG; the disease is congenital secretory chloride diarrhea 1.