A mutation of SARS was associated with APOB (beta = − 0.02; P = 5.92e−7), MAT2A with lymphocyte counts (beta = 1.34; P = 3.41E−28), and JCAD (odds ratio [OR] = 1.31; 95% confidence interval [CI] 1.18–1.46; P = 5.77e−7) as well as ARHGAP42 (OR = 2.08; 95% CI 1.65–2.59; P = 2.22e−9) were associated with risk of diabetes. The gene discussed is APOB; the disease is diabetes mellitus.