According to the GEPIA2 database query, we found that CMTM6 expression was upregulated in COAD (colon adenocarcinoma), GBM (glioblastoma multiforme), LAML (acute myeloid leukemia), LGG (brain lower grade glioma), OV (ovarian serous cystadenocarcinoma), PAAD (pancreatic adenocarcinoma), READ (rectum adenocarcinoma), STAD (stomach adenocarcinoma), THCA (thyroid carcinoma), and UCEC (uterine corpus endometrial carcinoma), especially in OV, compared with the corresponding normal tissues (Figure 1A). Here, CMTM6 is linked to colon adenocarcinoma.