Recently, some research studies explored the value of neutrophil gelatinase-associated lipocalin (NGAL), kidney injury molecule-1 (KIM-1), and insulin-like growth factor-binding protein-7 (IGFBP-7) in evaluating the risk of AKI and even diagnosing AKI among critically ill patients, such as TBI (3–10). Here, LCN2 is linked to acute kidney injury.