IGHE and eosinophilic gastrointestinal disease: Combined (mixed) IgE and cell mediated (delayed onset/chronic) include atopic dermatitis (AD), eosinophilic GI diseases (EGID) eosinophilic esophagitis (EoE), eosinophilic gastroenteritis (EGE) and eosinophilic proctocolitis (5).