Soare et al. (2018) reported the highly significant correlation of the ILC2/ILC3 ratio with disease activity indexes in psoriatic arthritis, suggesting the potential of ILC as a biomarker for immunological disease activity. Here, correlation analyses showed the strongest positive association between ILC1 counts and corresponding RAE scores in OLP (r = 0.7445, p < 0.0001), indicating that circulating ILC1s might serve as a promising molecular predictor of OLP disease severity. This evidence concerns the gene CCL27 and oral lichen planus.