In this study, we detected levels of ILC-related activation factors in OLP plasma and found that the expression levels of IL-12, IL-18, and IL-1β, which were dramatically elevated in OLP plasma, were consistent with that reported in OLP studies (Zhang et al., 2012; Huang et al., 2016; Seebauer et al., 2020). This evidence concerns the gene CCL27 and oral lichen planus.