LncRNA CCDC26 knocking down decreased the apoptosis of GIST cells treated with imatinib through upregulating insulin-like growth factor 1 receptor (IGF-1R), which acted in the apoptosis pathways (Li et al., 2018; Yan et al., 2019b; Zhang Y. et al., 2019). The gene discussed is IGF1R; the disease is gastrointestinal stromal tumor.