In training cohort, the univariate analysis identified significant differences in surgery days (P = 0.03), CMV IgM +ve associated BA (P < 0.001), ln (GGT) (P < 0.001), thickness of the fibrous portal plate (P < 0.001), LSM value (P < 0.001), Metavir score (P = 0.02), and multiple episodes of cholangitis (P < 0.001). Here, CD40LG is linked to cholangitis.