TRPV1 in KIRC, TRPV2 in LUSC, TRPV3 in BRCA, TRPV6 in LUAD and BRCA, while TRPV4 in KIRC and BRCA differed significantly across different cancer subtypes (P <0.05) (Figure 1C). The gene discussed is TRPV4; the disease is cancer.