Meanwhile, the hypomethylation of TRPV4, TRPV5, and TRPV6 in LGG, TRPV2 in KIRP, UVM, DLBC, GBM, and KIRC was associated with a poor prognosis (P <0.05) (Figure 4C). The gene discussed is TRPV2; the disease is glioblastoma.