GSEA performed using TCGA data revealed that several cancer-related pathways were linked to ITGA3 high expression, including apoptosis, cell cycle, chronic myeloid leukemia, ERBB signaling pathway, mitogen-activated protein kinase (MAPK) signaling pathway, melanoma, P53 signaling pathway, pathways in cancer, and small cell lung cancer. The gene discussed is WNK2; the disease is melanoma.