ENTPD1 and COVID-19: CD39 plasma levels at admission efficiently discriminated the COVID-19 patients who required ICU admission during their hospitalization, with an AUC-ROC curve of 0·732 (95%CI 0·613 to 0·883; P=0·0006) (Figure 2F) and an optimal Youden cut-off value of 49·52 pg/mL (Sensitivity 61·54%; Specificity 83·67%).