GPT and colitis: In addition, concerning neoadjuvant ICIs, the most common all-grade irAEs were rash (29%; 95% CI, 16%-46%), transaminitis (20%; 95% CI, 10%-36%), and AST increased (19%; 95% CI, 14%-26%) (Figure 3A), and the most common high-grade irAEs were gamma-glutamyltransferase increased (4%; 95% CI, 1%-8%), colitis (4%; 95% CI, 1%-8%), and alanine transaminase (ALT) increased (4%; 95% CI, 0-11%) (Figure 3B).