Among these enriched signaling pathways, the Hippo signaling pathway was the most significantly associated with YAP interaction DEGs, while other enriched signaling pathways included cell cycle and division-related pathways (cellular senescence, cell cycle, and oocyte meiosis), liver disease-associated pathways (hepatocellular carcinoma, hepatitis C, and hepatitis B), multiple cancer-related pathways (breast cancer, gastric cancer, colorectal cancer, prostate cancer, and endometrial cancer), and the PI3K-Akt signaling pathway, which is closely associated with tumor immunity. Here, YAP1 is linked to hepatitis B virus infection.