Six potential targets were identified in DLB vs. control including downregulation of neurosecretory protein VGF, neuronal pentraxin-2 (NPTX2), neuroendocrine convertase 2 (PCSK2), neuronal pentraxin receptor (NPTXR), upregulation of ubiquitin carboxyl-terminal hydrolase (USP14), and proteasome subunit beta type-7 (PSMB7) (73). This evidence concerns the gene PCSK2 and Lewy body dementia.