Dr. Gibbons presented a distinct approach to skin biopsy involving three punch biopsies from the distal leg, distal thigh, and posterior cervical region in people with PD and DLB, using a double-label immunofluorescence method to detect and colocalize both alpha-synuclein and neuronal markers (PGP 9.5) in thick sections (11, 24, 25). Here, SNCA is linked to Parkinson disease.