Recent studies demonstrated that IL-31 and TSLP appear to be partially involved not only in the pathogenesis of psoriasis, but also in the induction of itch in psoriasis (Nattkemper et al., 2018; Gago-Lopez et al., 2019; Gibbs et al., 2019; Suwarsa et al., 2019). The gene discussed is IL31; the disease is psoriasis.