To study the effect of RhoJ on GBM angiogenesis and growth in vivo, we subcutaneously injected U87 cells infected by plenti-RhoJ or plenti-con in NOD-SCID mice and found that the tumor tissues in plenti-RhoJ group grew faster, larger and heavier, compared with those in plenti-con group (Fig. 1C-E). This evidence concerns the gene RHOJ and neoplasm.