BCL2 and acute respiratory distress syndrome: Other cell types. Recent study reported that in alveoli, amid (ARDS) acute respiratory distress syndrome, stimulation of Piezo1 by mechanical stretching result in elevated intracellular Ca2+ evoked type II pneumocytes apoptosis, whereas, reduction in apoptosis was observed in the absence of Piezo1, which are in association with Bcl-2 pathway 153.