Previously, we reported that USP13 is strongly overexpressed in HGSOC tissues, and the depletion of USP13 selectively kills USP13-amplified human ovarian cancer cells and suppresses ovarian tumor growth in a xenograft mouse study, suggesting a critical role for USP13 in the survival and proliferation of ovarian cancer cells [21]. This evidence concerns the gene USP13 and ovarian neoplasm.