MRC1 and neoplasm: High protein expression of cytoplasmic IKKα was associated with increasing AJCC T stage (p = 0.022) but was not associated with patient age, sex, tumour location, nodal stage, tumour differentiation, venous invasion, margin involvement, tumour necrosis, proliferation index, tumour stroma percentage, inflammatory cell infiltrate (Klintrup-Mäkinen grade) or MMR status (Table 1).