LRRK2 and Parkinson disease: The LRRK2 level was found to be considerably increased in the PD patients, in comparison to the controls; the LRRK2 level also showed a significant rise in the early stage patients when compared to controls and late stage groups; as well there was no considerable difference in terms of the LRRK2 levels in the late stage groups of the PD patients, in comparison to the controls.