Subsequent to the detailed analysis of several datasets obtained from the GEO omnibus for possible diagnostic biomarkers involved in different phases of spermatogenesis, and in overall male infertility, the following genes/proteins were identified (INPP1, ATG9A, CCDC96, THEG, SPATA20, KRI1, CNTN2, KANTNB1, FBXO24, PRPPH, HEATR9, IQCN, FUZ, C9orf131, C20orf173, TMCO5A, GTSF1, ROPN1L, ADAD1, BANF2, TSSK1B, CRISP2, RIMBP3, LYZL2, CABS1). The gene discussed is CRISP2; the disease is male infertility.