The analysis of shared significant loci across infectious and non-infectious phenotypes in the UK Biobank cohort revealed associations between one of the SNPs identified for abdominal infections (rs570640158) located in the HLA region, and phenotypes related to infection, inflammatory and autoimmune diseases, including CRP, asthma (ICD-10 code J45), diabetes mellitus (E10, E11) and rheumatoid arthritis (M05, M06) (Fig. S3B). Here, CRP is linked to rheumatoid arthritis.