ABHD5 (αβ hydrolase domain-containing protein 5) is a highly conserved protein that plays diverse roles in lipid metabolism including lipolysis in adipose tissue and muscle1,2, lipid barrier formation in skin3,4, Hepatitis C Virus assembly and production5, and suppression of tumor progression in colon and prostate cancer6,7. The gene discussed is ABHD5; the disease is neoplasm.