Nonetheless, the RV144 CoR with V1V2 Abs has been buttressed by similar conclusions emanating from several studies of immunized NHPs in which protection, control, and/or delayed infection with SIV or SHIV were correlated with strong Ab responses to the V1V2 domain of gp120 (reviewed in Zolla-Pazner et al.8). Here, ITIH4 is linked to infection.