The box line diagram drawn, based on TESC expression data from GE3467 dataset in the Gene Expression Omnibus (GEO) database, showed that TESC was highly expressed in thyroid cancer samples (Fig. 2A), and similar results were seen in the thyroid cancer expression datasets from The Cancer Genome Atlas (TCGA) using the UALCAN database (http://ualcan.path.uab.edu/index.html) (Fig. 2B). This evidence concerns the gene TESC and thyroid gland carcinoma.