S100A8 and carcinoma: We selected four that were among the top differentially expressed proteins between the immune hot cluster vs. others (Supplementary Data 2c), had available antibodies applicable to FFPE; and had a practical scoring methodology on carcinoma cells by IHC; TAP1 (MHC class I), HLA-DQA1 (MHC class II), IFIT2 (type I interferon signaling) and S100A8 (Fig. 4b, c).