The Assessing Very Early Rheumatoid arthritis Treatment (AVERT) study of patients with early, active RA demonstrated the proportion of patients with Disease Activity Score in 28 joints (C-reactive protein) (DAS28[CRP])-defined remission (DAS28[CRP] <2.6) was significantly higher following 12 months of treatment with abatacept plus methotrexate (MTX) versus MTX alone [17]. This evidence concerns the gene CRP and rheumatoid arthritis.