While its role has been elucidated in chronic myeloid leukemia (CML) cells (e.g. [63]) and in acute lymphoblastic leukemia [64], to our knowledge no studies addressing the mechanism linking HERG to CLL B lymphocyte proliferation or pharmacological studies targeting HERG in CLL B cells were performed. The gene discussed is KCNH2; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.